Assay development
Sample preparation, chromatographic separation, ionization optimization, and calibration strategy for target sensitivity.
← Bioanalysis ServicesLC-MS/MS Quantitation
Small Molecule Bioanalysis
Sensitive, selective quantification of drugs and metabolites in biological matrices for discovery, toxicology, and clinical development programs.
PlasmaSerumUrineTissueGLP Validation
Core Introduction
Methods matched to the molecule and study decision.
RebirthBiology develops and validates LC-MS/MS assays for small molecules and metabolites, emphasizing reliable extraction, matrix control, calibration performance, and reproducible sample analysis.
Validation
Accuracy, precision, selectivity, sensitivity, recovery, matrix effect, stability, and dilution integrity.
Sample analysis
Regulated batch runs with QC acceptance, repeat rules, incurred sample reanalysis, and traceable reporting.
Metabolite support
Quantitative or semi-quantitative workflows for active, major, or safety-relevant metabolites.
Why Choose
Bioanalytical rigor without slowing the program.
High-throughput platforms
Instrument capacity and standardized run review keep discovery and clinical timelines moving.
Matrix expertise
Assays are optimized for biological complexity, anticoagulants, endogenous interferences, and low-volume samples.
PK-ready outputs
Data packages are structured for direct handoff to pharmacokinetic and statistical evaluation.
Need a reliable concentration-time profile?
Send analyte details, expected range, matrix, species, and study design.
Start Small Molecule Bioanalysis