← Bioanalysis ServicesOligonucleotides & Genetic Medicines

Nucleic Acids

Bioanalytical and quality-oriented support for oligonucleotides, siRNA, antisense candidates, mRNA-related constructs, and nucleic-acid based therapeutics.

OligonucleotidesHybridizationLC-MSqPCRLNP

Assays for sequence-driven medicines.

Nucleic acid therapeutics demand careful control of sequence specificity, extraction recovery, nuclease stability, and matrix effects. rebirthBiology configures platforms around analyte chemistry and required sensitivity.

Hybridization assays

Sensitive quantification using capture and detection strategies tailored to sequence and modifications.

LC-MS workflows

Mass-based characterization and quantitation support for oligonucleotide purity, metabolites, and impurities.

qPCR / molecular readouts

Platform support for vector, transcript, or sequence-related measurements where applicable.

Formulation support

Analytical testing around LNP-associated attributes, encapsulation questions, and stability-indicating needs.

Why Choose

Specificity first, sensitivity always.

Sequence awareness

Assays are selected to manage cross-hybridization, shortened metabolites, and modified backbones.

Platform flexibility

Hybridization, LC-MS, and molecular methods can be combined to answer different questions.

Development continuity

Bioanalysis and CMC perspectives are aligned for oligonucleotide programs.

Develop a nucleic acid assay strategy.

Send sequence class, modifications, matrix, expected concentration, and decision stage.

Start Nucleic Acid Support