Hybridization assays
Sensitive quantification using capture and detection strategies tailored to sequence and modifications.
Bioanalytical and quality-oriented support for oligonucleotides, siRNA, antisense candidates, mRNA-related constructs, and nucleic-acid based therapeutics.
Nucleic acid therapeutics demand careful control of sequence specificity, extraction recovery, nuclease stability, and matrix effects. rebirthBiology configures platforms around analyte chemistry and required sensitivity.
Sensitive quantification using capture and detection strategies tailored to sequence and modifications.
Mass-based characterization and quantitation support for oligonucleotide purity, metabolites, and impurities.
Platform support for vector, transcript, or sequence-related measurements where applicable.
Analytical testing around LNP-associated attributes, encapsulation questions, and stability-indicating needs.
Assays are selected to manage cross-hybridization, shortened metabolites, and modified backbones.
Hybridization, LC-MS, and molecular methods can be combined to answer different questions.
Bioanalysis and CMC perspectives are aligned for oligonucleotide programs.
Send sequence class, modifications, matrix, expected concentration, and decision stage.
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